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At 20 days of life, the heart of an evolving human being looks like a worm... At 25 days... a clear-cut... single pump... In a sense, we mirror... a … - Gerald Buckberg
" "At 20 days of life, the heart of an evolving human being looks like a worm... At 25 days... a clear-cut... single pump... In a sense, we mirror... a fish... At 30 days, the embryologic heart contains a patent ventricular septal defect and an atrial septal defect... we resemble the amphibian and the reptile... Finally, at 50 days... an intact atrial and ventricular septum.... our cardiac evolution encompasses 1 billion years of the phylogenetic development.
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About Gerald Buckberg
(September 29, 1935 - September 20, 2018) was a Distinguished Professor of Surgery, Division of Cardiothoracic Surgery, at the . His research interests initially centered in the area of myocardial protection and led to the introduction of blood , which is currently used by over 85% of surgeons in the United States and 75% of surgeons worldwide for adult and pediatric heart operations. He was a member of multiple surgical societies, including the , , and the .
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Additional quotes by Gerald Buckberg
[P]acemakers elevate the heart rate... but they don’t always reproduce a normal heartbeat. ...[I]f the pacemaker leads are placed directly in ventricular muscle... the natural electrical system is not utilized. ...[T]here is loss of the natural twisting motion needed for efficient contraction.
It may even cause heart function to worsen and produce heart failure in patients with dilated hearts. In other patients, fatigue will not improve, and shortness of breath will not get better.
Clearly it’s important not to injure the septum during operations. So why is it happening repeatedly? ...[L]ikely ...improper myocardial protection (the technique used to protect the heart... that was my initial major medical discovery and quickly adopted worldwide). We... tested 119 consecutive patients and found no septum damage when protection was done correctly. ...Successful protection involves ...the cardioplegic solution and adopting a correct delivery strategy. ...[I]f surgeons are to prevent the all-too-frequent injury to the heart’s vital septum, they must avoid taking shortcuts that compromise this essential combination.
[O]ne of the great anguishes in medicine is its inability to treat right (ventricle) heart failure... [due to] an absence of understanding how the normal right ventricle... functions. Conventional views hold... a 400-year-old belief that the right ventricle compresses like "a "... But... that... only accounts for 20% of the... pumping... The shortening of the septum... produces 80% of its function. ...Torrent-Guasp’s "helix and wrap"... model clarifies why... [m]odern 3-D imaging confirms that the septum portion of the helix... twists to pump... from the right ventricle to the lungs... In animal testing, we further verified [this].
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