To the extent that genomes can be thought of as compressed encodings of biological structures, they are spectacularly efficient. All the trillions of… - Gary F. Marcus

Instead, in our world, nature's contribution to development comes not by providing a finely detailed sketch of a finished product, but by providing a complex system of self-regulating recipes. Those recipes provide for many different things-from the construction of enzymes and structural proteins to the construction of motors, transporters, receptors, and regulatory proteins-and thus there is no single, easily characterizable genetic contribution to the mind. In the ongoing, everyday functioning of the brain, genes supervise the construction of neurotransmitters, the metabolism of glucose, and the maintenance of synapses. In early development, they help to lay down a rough draft, guiding the specialization and migration of cells as well as the initial pattern of wiring. In synaptic strengthening, genes are a vital participant in a mechanism by which experience can alter the wiring of the brain (thereby influencing the way that an organism interprets and responds to the environment). There are at least as many different genetic contributions to the mind and brain as there are genes; each contributes by regulating a different process.

In essence, the bee's azimuth system acts like a sundial run in reverse, and like a sundial, it has to be calibrated. A sundial, which must be oriented with respect to a known compass direction, calculates the time of day based on where the sun is; the navigational centers in the bee's brain calculate where the sun should be based on the time of day. As a consequence, the one thing that bees can't cope with is the discalibration that results from jet lag. In a famous 1960s experiment, Max Renner packed up a hive of bees in Long Island, New York, flew them to Davis, California, and tested their ability to navigate with the sun as a landmark. The jetlagged bees consistently misoriented themselves by 45 degrees, precisely as though they believed it was three hours later. The complex circuitry that allows the bee to use the sun as a guide is built in, but it is not that genes trump the environment (or the other way around). Instead, genes enable creatures to make sensible use of their particular environment. Learning is not the antithesis of innateness but one of its most important products.

the time when we tend to notice that we need toilet paper tends not to be the moment when we are in a position to buy it.