[Ambitious men] may not cease, but as a dog in a wheel, a bird in a cage, or a squirrel in a chain, so Budaeus compares them; they climb and climb st… - Robert Burton

What physic, what chirurgery, what wealth, favor, authority can relieve, bear out, assuage, or expel a troubled conscience? A quiet mind cureth all them, but all they cannot comfort a distressed soul: who can put to silence the voice of desperation?

Melancholy and despair, though often, do not always concur; there is much difference: melancholy fears without a cause, this upon great occasion; melancholy is caused by fear and grief, but this torment procures them and all extremity of bitterness.

[Desire] is a perpetual rack, or horsemill, according to Austin, still going round as in a ring.