His contributions to condensed matter physics were largely on fundamental questions, establishing the principles of this subject. Most of this work w… - Rudolf Peierls

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His contributions to condensed matter physics were largely on fundamental questions, establishing the principles of this subject. Most of this work was done during the years 1928–37, but much of it could not be tested until the experimental techniques needed for this had become sufficiently developed. ...
Rudolf Peierls's work in nuclear physics began in 1933, when James Chadwick challenged him and Hans Bethe to explain his first measurements of the cross-section for photo-disintegration of the deuteron. Peierls's experience in this field developed rapidly within the next few years, on both practical questions and academic research, to the point where he and Otto Frisch could confidently conclude that the construction of an atomic bomb would be quite possible using ²³⁵U, which could be obtained obtained from natural uranium by a feasible separation process, and they pointed this out in the famous Frisch-Peierls Memorandum of 1940 which they sent to the British government. This led to the Atomic Bomb Project, at first in Britain under the name "Tube Alloys Project" and later in USA as the "Manhattan District Project", which many of the UK scientists, including both Peierls and Frisch, were sent to join at the end of 1943.