The threat lies in the realization that in our universe the security of stable, permanent rules are gone forever. We are living in a dangerous and un… - Ilya Prigogine

Given my interest in the concept of time, it was only natural that my attention was focused on the second principle, as I felt from the start that it would introduce a new, unexpected element into the description of physical world evolution. No doubt it was the same impression illustrious physicists such as Boltzmann and Planck would have felt before me. A huge part of my scientific career would then be devoted to the elucidation of macroscopic as well as microscopic aspects of the second principle, in order to extend its validity to new situations, and to the other fundamental approaches of theoretical physics, such as classical and quantum dynamics.

The problem of time in physics and chemistry is closely related to the formulation of the second law of thermodynamics. Therefore another possible title of this lecture could have been: “the macroscopic and microscopic aspects of the second law of thermodynamics”

The denial of becoming by physics estranged science from philosophy... [and] became a dogmatic assertion directed against all those (chemists, biologists, physicians) for whom a qualitative diversity existed in nature... Today we believe that the epoch of certainties and absolute oppositions is over. Physicists belong to their culture, to which, in their turn, they make an essential contribution.