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" "Since all models are wrong the scientist cannot obtain a "correct" one by excessive elaboration. On the contrary following William of Occam he should seek an economical description of natural phenomena. Just as the ability to devise simple but evocative models is the signature of the great scientist so overelaboration and overparameterization is often the mark of mediocrity.
George Edward Pelham Box (October 18, 1919 – March 28, 2013) was a British mathematician and professor of statistics at the University of Wisconsin, and a pioneer in the areas of quality control, , design of experiments and . He was the son-in-law of Sir Ronald Fisher.
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A mechanistic model has the following advantages: 1. It contributes to our scientific understanding of the phenomenon under study. 2. It usually provides a better basis for extrapolation (at least to conditions worthy of further experimental investigation if not through the entire range of all input variables). 3. It tends to be parsimonious (i.e, frugal) in the use of parameters and to provide better estimates of the response
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