The first study was on proguanil, a prophylactic antimalarial in healthy and sickle cell individuals. The study found that in persons with sickle cel… - Chinedum Babalola

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The first study was on proguanil, a prophylactic antimalarial in healthy and sickle cell individuals. The study found that in persons with sickle cell, about one per cent of them breakdown the drug slowly while it was five per cent in healthy persons. This shows that there is genetic difference between the two groups of people.

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About Chinedum Babalola

Chinedum Peace Babalola (née Anyabuike) FAS, FAAS is a Nigerian Professor of Pharmaceutical chemistry and Pharmacokinetics. She teaches Pharmacy at the University of Ibadan, FAS, and FAAS while also being the first Vice Chancellor of Chrisland University, Nigeria

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Work on quinine suppository has been on for so many years. Preliminary studies on the quinine suppository in rabbits indicated that it had antimalarial properties. However, the bioavailability is low. At the moment, one of our investigators is currently working in the USA on increasing its bioavailability to get an optimum product that will release the necessary level that they need. This will then be followed by more clinical trials.

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This is called adverse drug reaction and it could occur with the intake of many drugs because no drug is 100 per cent safe. A particular one is the hypersensitivity to sulpha-containing drugs. It also occurs with drugs that contain amino compounds

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