There is no fixed, eternal frame to the universe to define what may or may not exist. - Lee Smolin

In both quantum theory and general relativity, we encounter predictions of physically sensible quantities becoming infinite. This is likely the way that nature punishes impudent theorists who dare to break her unity. ...If infinities are signs of missing unification, a unified theory will have none. It will be what we call a finite theory.

In string theory one studies strings moving in a fixed classical spacetime. ...what we call a background-dependent approach. ...One of the fundamental discoveries of Einstein is that there is no fixed background. The very geometry of space and time is a dynamical system that evolves in time. The experimental observations that energy leaks from binary pulsars in the form of gravitational waves—at the rate predicted by general relativity to the... accuracy of eleven decimal places—tell us that there is no more a fixed background of spacetime geometry than there are fixed crystal spheres holding the planets up.

Many of us believed in the possibility of a principled explanation for the laws of nature. We hoped to discover a short list of principles, which could be realized in a unique theory, which would retrodict the standard model and uniquely predict the physics to be discovered beyond it. The shocking implication of the results of Strominger reported in 1986 was that it was not to be, at least within the confines of string theory. ...String theory offered more, however... It offered the promise of a setting in which the different perturbative string theories are realized as expansions around solutions of a still more fundamental theory. ...That more fundamental theory would have to be background independent...