If a rat is a good model for your emotional life, you're in big trouble. - Robert Sapolsky

We're only a couple of hundreds of years into understanding that epilepsy is a neurological disease and not a demonic possession. We're only about 50 years into understanding that certain types of learning disabilities are micro malformations in the cortex in people with dyslexia and not laziness or lack of motivation. The vast majority of these factoids [presented in the book] are 10, 20 years old, and all that's gonna happen is we're gonna learn more and more of that stuff. And what we're going to learn more and more is to recognise extents to which we're biological organisms and our behaviours have to be evaluated in that realm. For my money, what that eventually does is make words like "soul" or "evil" utterly absurd and medieval, but it also makes words like "punishment" or "justice" very questionable, as well. I think it will require an enormous reshaping of how we think we deal with the most damaging of human behaviours, because none of it can be thought of outside the context of biology.

Why do we have schizophrenia in every culture on this planet? From an evolutionary perspective, schizophrenia is not a cool thing to have. ... Schizophrenia is not an adaptive trait. You can show this formally: schizophrenics have a lower rate of leaving copies of their genes in the next generation than unaffected siblings. By the rules, by the economics of evolution, this is a maladaptive trait. Yet, it chugs along at a one to two percent rate in every culture on this planet. So what's the adaptive advantage of schizophrenia? It has to do with a classic truism — this business that sometimes you have a genetic trait which in the full-blown version is a disaster, but the partial version is good news.

The far-from-original point I will try to make now should seem obvious: There is an unsettling similarity between the rituals of the obsessive-compulsive and the rituals of the observantly religious.