There isn't much debate on the downsides of consumption of animal protein. Study after study has demonstrated that heavily animal-based diets are ass… - David A. Sinclair

We can't prevent all DNA damage — and we wouldn't want to because it's essential for the function of the immune system and even for consolidating our memories57 — but we do want to prevent extra damage. And there's a lot of extra damage to be had out there. Cigarettes, for starters. There aren't many legal vices out there that are worse for your epigenome than the deadly concoction of thousands of chemicals smokers put into their bodies every day. There's a reason why smokers seem to age faster: they do age faster. The DNA damage that results from smoking keeps the DNA repair crews working overtime, and likely the result is the epigenetic instability that causes aging. And although I'm not likely to be the first person you'll hear this from, it nonetheless bears repeating: smoking is not a private, victimless activity. The levels of DNA-damaging aromatic amines in cigarette smoke are about fifty to sixty times as high in secondhand as in firsthand smoke.58 If you do smoke, it is worth trying to quit.

Don't be disheartened by my claim that we are the biological equivalent of an old DVD player. This is actually good news. If Szilard had turned out to be right about mutations causing aging, we would not be able to easily address it, because when information is lost without a backup, it is lost for good. Ask anyone who's tried to play or restore content from a DVD that's had an edge broken off: what is gone is gone. But we can usually recover information from a scratched DVD. And if I am right, the same kind of process is what it will take to reverse aging.

Aging is controlled by single genes
Aging is slowed by adversity
Aging regulators can be modulated by small molecules
Aging is slowed by eating stressed plants
Aging is largely epigenetic noise
Cellular damage accelerates epigenetic age
Aging is a disease
Aging is reversible