My dad is actually a manic depressive, which is very exciting half the time. - Marc Maron

I think, in most cases, the difference between depression and disappointment is your level of commitment.

How many friends do you really have, seriously? You people...like "I have lots of friends." You don't. You have a lot of shallow relationships with people that talk behind your back and you call that drama a life because you hate your job.

Do you think Beethoven had any inkling in even the darkest recesses of his unconscious, when he was deaf and sweating over his Fifth Symphony, that one day it would emit from some idiot’s pocket, and the response would be "Fuck, it’s my mom"?