Though its fame is much restricted by its specialized nature, there is no doubt that Panini's grammar is one of the greatest intellectual achievement… - Panini

Pāṇini had before him a list of irregularly formed words, which survives, in a somewhat modified form, as the Uṇādi Sūtra. There are also two appendixes to which Pāṇini refers: one is the Dhātupāṭha, "List of Verbal Roots," containing some 2000 roots, of which only about 800 have been found in Sanskrit literature, and from which about fifty Vedic verbs are omitted; the second is the Gaṇapāṭha, or "List of Word-Groups," to which certain rules apply. These gaṇas were metrically arranged in the Gaṇaratna-mahodadhi, composed by Vardhamāna in 1140 A.D.

The word `Sanskrit' means “prepared, pure, refined or prefect”. It was not for nothing that it was called the `devavani' (language of the Gods). It has an outstanding place in our culture and indeed was recognized as a language of rare sublimity by the whole world. Sanskrit was the language of our philosophers, our scientists, our mathematicians, our poets and playwrights, our grammarians, our jurists, etc. In grammar, Panini and Patanjali (authors of Ashtadhyayi and the Mahabhashya) have no equals in the world; in astronomy and mathematics the works of Aryabhata, Brahmagupta and Bhaskara opened up new frontiers for mankind, as did the works of Charaka and Sushruta in medicine.

The author of the oldest extant Sanskrit grammar was Panini, a native of extreme north-west India, ... His work consists of nearly 4000 aphorisms, each of which owing to the extreme conciseness of the style, generally consists of not more than two or three words. Hence, the whole grammar could be printed within the compass of about thirty-five octavo pages. Yet it describes the entire Sanskrit language with a completeness which has never been equalled elsewhere. Thus it is at once the shortest and the fullest grammar in the world.