Insight must precede application. - Max Planck

It [science] has as its highest principle and most coveted aim the solution of the problem to condense all natural phenomena which have been observed and are still to be observed into one simple principle, that allows the computation of past and more especially of future processes from present ones. ...Amid the more or less general laws which mark the achievements of physical science during the course of the last centuries, the principle of least action is perhaps that which, as regards form and content, may claim to come nearest to that ideal final aim of theoretical research.

Nature never undertakes any change unless her interests are served by an increase in entropy.

A new scientific truth does not generally triumph by persuading its opponents and getting them to admit their errors, but rather by its opponents gradually dying out and giving way to a new generation that is raised on it. … An important scientific innovation rarely makes its way by gradually winning over and converting its opponents: it rarely happens that Saul becomes Paul. What does happen is that its opponents gradually die out, and that the growing generation is familiarized with the ideas from the beginning: another instance of the fact that the future lies with the youth.