As a species, we are living much longer than ever. But not much better. Not at all. Over the past century we have gained additional years, but not ad… - David A. Sinclair

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As a species, we are living much longer than ever. But not much better. Not at all. Over the past century we have gained additional years, but not additional life — not life worth living anyway.5

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Alternative Names: David Andrew Sinclair Dr. David Sinclair David A Sinclair David Sinclair
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Small numbers of senescent cells can cause widespread havoc. Even though they stop dividing, they continue to release tiny proteins called cytokines that cause inflammation and attract immune cells called macrophages that then attack the tissue. Being chronically inflamed is unhealthy: just ask someone with multiple sclerosis, inflammatory bowel disease, or psoriasis. All these diseases are associated with excess cytokine proteins.

Aunque no es inmortal, el tiburón boreal Somniosus microcephalus sigue siendo un animal impresionante y está mucho más emparentado con nosotros. Es casi del mismo tamaño que un tiburón blanco y no alcanza la madurez sexual hasta los ciento cincuenta años. Los investigadores creen que el océano Ártico podría ser el hogar de los tiburones boreales que nacieron antes de que Colón se perdiera en el Nuevo Mundo. Según la datación por carbono 14, un ejemplar enorme podría haber vivido más de quinientos diez años, al menos hasta que los científicos lo capturaron para poder dictaminar su edad. El hecho de que las células de este tiburón envejezcan o no es un debate científico abierto; muy pocos biólogos habían estudiado al S. microcephalus hasta hace unos años. Como mínimo, este longevo vertebrado experimenta el proceso del envejecimiento muy pero que muy despacio.

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I eat a lot of plants and try to avoid eating other mammals, even though they do taste good. If I work out, I will eat meat. • I don't smoke. I try to avoid microwaved plastic, excessive UV exposure, X-rays, and CT scans. • I try to stay on the cool side during the day and when I sleep at night. • I aim to keep my body weight or BMI in the optimal range for healthspan, which for me is 23 to 25.

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