Let your self go. If you can approach the world's complexities, both its glories and its horrors, with an attitude of humble curiosity, acknowledging that however deeply you have seen, you have only scratched the surface, you will find worlds within worlds, beauties you could not heretofore imagine, and your own mundane preoccupations will shrink to proper size, not all that important in the greater scheme of things.' Keeping that awestruck vision of the world ready to hand while dealing with the demands of daily living is no easy exercise, but it is definitely worth the effort, for if you can stay centered, and engaged, you will find the hard choices easier, the right words will come to you when you need them, and you will be a better person. That, I propose, is the secret to spirituality, and it has nothing at all to do with believing in an immortal soul, or in anything supernatural.

[T]he physicist Steven Weinberg, in Dreams of a Final Theory (1992) … distinguishes between uncompromising reductionism (a bad thing) and compromising reductionism (which he ringingly endorses). Here is my own version. We must distinguish reductionism, which is in general a good thing, from greedy reductionism, which is not. The difference, in the context of Darwin's theory, is simple: greedy reductionists think that everything can be explained without cranes; good reductionists think that everything can be explained without skyhooks.

[T]he Capgras delusion [is] a bizarre affliction that occasionally strikes human beings who have suffered brain damage. The defining mark of the Capgras delusion is the sufferer's conviction that a close acquaintance (usually a loved one) has been replaced by an impostor who looks like (and sounds like, and acts like) the genuine companion, who has mysteriously disappeared! … What is particularly surprising about these cases is that they don't depend on subtle disguises and fleeting glimpses. On the contrary, the delusion persists even when the target individual is closely scrutinized by the [Capgras sufferer], and is even pleading for recognition. Capgras sufferers have been known to murder their spouses, so sure are they that these look-alike interlopers are trying to step into their shoes — into whole lives — that are not rightfully theirs! There can be no doubt that in such a sad case, the [sufferer] in question has deemed true some very specific proposition of nonidentity: This man is not my husband; this man is a qualitatively similar to my husband as ever can be, and yet he is not my husband. Of particular interest to us is the fact that people suffering from such a delusion can be quite unable to say why they are so sure.

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Of all the mind tools we acquire in the course of furnishing our brains from the stockpiles of culture, none are more important, of course, than words — first spoken, then written. Words make us more intelligent by making cognition easier, in the same way (many times multiplied) that beacons and landmarks make navigation in the world easier for simple creatures. Navigation in the abstract multidimensional world of ideas is simply impossible without a huge stock of movable, memorable landmarks that can be shared, criticized, recorded, and looked at from different perspectives.

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Evolution is all about processes that almost never happen. Every birth in every lineage is a potential speciation event, but speciation almost never happens, not once in a million births. Mutation in DNA almost never happens — not once in a trillion copings — but evolution depends on it. Take the set of infrequent accidents — things that almost never happen — and sort them into the happy accidents, the neutral accidents, and the fatal accidents; amplify the effects of the happy accidents — which happens automatically when you have replication and competition — and you get evolution.

Political correctness, in the extreme versions worthy of the name, is antithetical to almost all surprising advances in thought. We might call it eumemics, since it is, like the extreme eugenics of Social Darwinists, an attempt to impose myopically derived standards of safety and goodness on the bounty of nature. Few today — but there are a few — would brand all genetic counseling, all genetic policies, with the condemnatory title of eugenics.

The term that is most often bandied about in these conflicts, typically as a term of abuse, is "reductionism." Those who yearn for skyhooks call those who eagerly settle for cranes "reductionists"... The problem is that there are both bland readings and preposterous readings of any such claim. According to the bland readings, it is possible (and desirable) to unify chemistry and physics, biology and chemistry, and, yes, even the social sciences and biology... According to the preposterous readings, reductionists want to abandon the principles, theories, vocabulary, laws of the higher-level sciences, in favor of the lowerlevel terms. A reductionist dream, on such a preposterous reading, might be to write "A Comparison of Keats and Shelley from the Molecular Point of View"... Probably nobody is a reductionist in the preposterous sense, and everybody should be a reductionist in the bland sense, so the "charge" of reductionism is too vague to merit a response.

Experience teaches...that there is no such thing as a thought experiment so clearly presented that no philosopher can misinterpret it...

From what can "ought" be derived. The most compelling answer is this: ethics must be somehow based on an appreciation of human nature — on a sense of what a human being is or might be, and on what a human being might want to have or want to be. If that is naturalism, then naturalism is no fallacy. No one could seriously deny that ethics is responsive to such facts about human nature. We may just disagree about where to look for the most compelling facts about human nature -n novels, in religious texts, in psychological experiments, in biological or anthropological investigations. The fallacy is not naturalism but, rather, any simple-minded attempt to rush from facts to values. In other words, the fallacy is greedy reductionism of values to facts, rather than reductionism considered more circumspectly, as the attempt to unify our world-view so that out ethical principles don't clash irrationally with the way the world is.

We used to think that secrecy was perhaps the greatest enemy of democracy, and as long as there was no suppression or censorship, people could be trusted to make the informed decisions that would preserve our free society, but we have learned in recent years that the techniques of misinformation and misdirection have become so refined that, even in an open society, a cleverly directed flood of misinformation can overwhelm the truth, even though the truth is out there, uncensored, quietly available to anyone who can find it.

Goodness comes in many forms, not just medicine and science. Thank goodness for the music of, say, Randy Newman, which could not exist without all those wonderful pianos and recording studios, to say nothing of the musical contributions of every great composer from Bach through Wagner to Scott Joplin and the Beatles. Thank goodness for fresh drinking water in the tap, and food on our table. Thank goodness for fair elections and truthful journalism. If you want to express your gratitude to goodness, you can plant a tree, feed an orphan, buy books for schoolgirls in the Islamic world, or contribute in thousands of other ways to the manifest improvement of life on this planet now and in the near future. Or you can thank God — but the very idea of repaying God is ludicrous. What could an omniscient, omnipotent Being (the Man Who has Everything?) do with any paltry repayments from you? (And besides, according to the Christian tradition God has already redeemed the debt for all time, by sacrificing his own son. Try to repay that loan!) Yes, I know, those themes are not to be understood literally; they are symbolic. I grant it, but then the idea that by thanking God you are actually doing some good has got to be understood to be just symbolic, too. I prefer real good to symbolic good. Still, I excuse those who pray for me. I see them as like tenacious scientists who resist the evidence for theories they don't like long after a graceful concession would have been the appropriate response. I applaud you for your loyalty to your own position — but remember: loyalty to tradition is not enough. You've got to keep asking yourself: What if I'm wrong? In the long run, I think religious people can be asked to live up to the same moral standards as secular people in science and medicine.

The evidence of evolution pours in, not only from geology, paleontology, biogeography, and anatomy (Darwin's chief sources), but from molecular biology and every other branch of the life sciences. To put it bluntly but fairly, anyone today who doubts that the variety of life on this planet was produced by a process of evolution is simply ignorant — inexcusably ignorant, in a world where three out of four people have learned to read and write. Doubts about the power of Darwin's idea of natural selection to explain this evolutionary process are still intellectually respectable, however, although the burden of proof for such skepticism has become immense...

There is a familiar trio of reactions by scientists to a purportedly radical hypothesis: (a) "You must be out of your mind!", (b) "What else is new? Everybody knows that!", and, later — if the hypothesis is still standing — (c) "Hmm. You *might* be on to something!" Sometimes these phases take years to unfold, one after another, but I have seen all three emerge in near synchrony in the course of a half-hour's heated discussion following a conference paper.

A neurosurgeon once told me about operating on the brain of a young man with epilepsy. As is customary in this kind of operation, the patient was wide awake, under only local anesthesia, while the surgeon delicately explored his exposed cortex, making sure that the parts tentatively to be removed were not absolutely vital by stimulating them electrically and asking the patient what he experienced. Some stimulations provoked visual flashes or hand-raisings, others a sort of buzzing sensation, but one spot produced a delighted response from the patient: "It's 'Outta Get Me' by Guns N' Roses, my favorite heavy metal [sic] band!" I asked the neurosurgeon if he had asked the patient to sing or hum along with the music, since it would be fascinating to learn how "high fidelity" the provoked memory was. Would it be in exactly the same key and tempo as the record? Such a song (unlike "Silent Night") has one canonical version, so we could simply have superimposed a recording of the patient's humming with the standard record and compare the results. Unfortunately, even though a tape recorder had been running during the operation, the surgeon hadn't asked the patient to sing along. "Why not?" I asked, and he replied: "I hate rock music!" Later in the conversation the neurosurgeon happened to remark that he was going to have to operate again on the same young man, and I expressed the hope that he would just check to see if he could restimulate the rock music, and this time ask the fellow to sing along. "I can't do that," replied the neurosurgeon, "since I cut out that part." "It was part of the epileptic focus?" I asked, and he replied, "No, I already told you – I hate rock music."