Do I worship modern medicine? Is science my religion? Not at all; there is no aspect of modern medicine or science that I would exempt from the most rigorous scrutiny, and I can readily identify a host of serious problems that still need to be fixed. That's easy to do, of course, because the worlds of medicine and science are already engaged in the most obsessive, intensive, and humble self-assessments yet known to human institutions, and they regularly make public the results of their self-examinations. Moreover, this open-ended rational criticism, imperfect as it is, is the secret of the astounding success of these human enterprises. There are measurable improvements every day.

[T]he physicist Steven Weinberg, in Dreams of a Final Theory (1992) … distinguishes between uncompromising reductionism (a bad thing) and compromising reductionism (which he ringingly endorses). Here is my own version. We must distinguish reductionism, which is in general a good thing, from greedy reductionism, which is not. The difference, in the context of Darwin's theory, is simple: greedy reductionists think that everything can be explained without cranes; good reductionists think that everything can be explained without skyhooks.

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Goodness comes in many forms, not just medicine and science. Thank goodness for the music of, say, Randy Newman, which could not exist without all those wonderful pianos and recording studios, to say nothing of the musical contributions of every great composer from Bach through Wagner to Scott Joplin and the Beatles. Thank goodness for fresh drinking water in the tap, and food on our table. Thank goodness for fair elections and truthful journalism. If you want to express your gratitude to goodness, you can plant a tree, feed an orphan, buy books for schoolgirls in the Islamic world, or contribute in thousands of other ways to the manifest improvement of life on this planet now and in the near future. Or you can thank God — but the very idea of repaying God is ludicrous. What could an omniscient, omnipotent Being (the Man Who has Everything?) do with any paltry repayments from you? (And besides, according to the Christian tradition God has already redeemed the debt for all time, by sacrificing his own son. Try to repay that loan!) Yes, I know, those themes are not to be understood literally; they are symbolic. I grant it, but then the idea that by thanking God you are actually doing some good has got to be understood to be just symbolic, too. I prefer real good to symbolic good. Still, I excuse those who pray for me. I see them as like tenacious scientists who resist the evidence for theories they don't like long after a graceful concession would have been the appropriate response. I applaud you for your loyalty to your own position — but remember: loyalty to tradition is not enough. You've got to keep asking yourself: What if I'm wrong? In the long run, I think religious people can be asked to live up to the same moral standards as secular people in science and medicine.

I have grown accustomed to the disrespect expressed by some of the participants for their colleagues in the other disciplines. "Why, Dan," ask the people in artificial intelligence, "do you waste your time conferring with those neuroscientists? They wave their hands about 'information processing' and worry about where it happens, and which neurotransmitters are involved, but they haven't a clue about the computational requirements of higher cognitive functions." "Why," ask the neuroscientists, "do you waste your time on the fantasies of artificial intelligence? They just invent whatever machinery they want, and say unpardonably ignorant things about the brain." The cognitive psychologists, meanwhile, are accused of concocting models with neither biological plausibility nor proven computational powers; the anthropologists wouldn't know a model if they saw one, and the philosophers, as we all know, just take in each other's laundry, warning about confusions they themselves have created, in an arena bereft of both data and empirically testable theories. With so many idiots working on the problem, no wonder consciousness is still a mystery. All these charges are true, and more besides, but I have yet to encounter any idiots. Mostly the theorists I have drawn from strike me as very smart people – even brilliant people, with the arrogance and impatience that often comes with brilliance – but with limited perspectives and agendas, trying to make progress on the hard problems by taking whatever shortcuts they can see, while deploring other people's shortcuts. No one can keep all the problems and details clear, including me, and everyone has to mumble, guess and handwave about large parts of the problem.

We alone can be wracked with doubt, and we alone have been provoked by that epistemic itch to seek a remedy: better truth-seeking methods. Wanting to keep better track of our food supplies, our territories, our families, our enemies, we discovered the benefits of talking it over with others, asking questions, passing on lore. We invented culture. Then we invented measuring, and arithmetic, and maps, and writing. These communicative and recording innovations come with a built-in ideal: truth. The point of asking questions is to find true answers; the point of measuring is to measure accurately; the point of making maps is to find your way to your destination. … In short, the goal of truth goes without saying, in every human culture.

..the point of a randomizing device like a coin flip, [is] to make the result uncontrollable by making it sensitive to so many variables that no feasible, finite list of conditions can be singled out as the cause.

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Animals are not just herbivores or carnivores. They are, in the nice coinage of the psychologist George Miller, informavores.

One thing in particular struck me when I compared the medical world on which my life now depended with the religious institutions I have been studying so intensively in recent years. One of the gentler, more supportive themes to be found in every religion (so far as I know) is the idea that what really matters is what is in your heart: if you have good intentions, and are trying to do what (God says) is right, that is all anyone can ask. Not so in medicine! If you are wrong —especially if you should have known better — your good intentions count for almost nothing. And whereas taking a leap of faith and acting without further scrutiny of one's options is often celebrated by religions, it is considered a grave sin in medicine. A doctor whose devout faith in his personal revelations about how to treat aortic aneurysm led him to engage in untested trials with human patients would be severely reprimanded if not driven out of medicine altogether. There are exceptions, of course. A few swashbuckling, risk-taking pioneers are tolerated and (if they prove to be right) eventually honored, but they can exist only as rare exceptions to the ideal of the methodical investigator who scrupulously rules out alternative theories before putting his own into practice. Good intentions and inspiration are simply not enough. In other words, whereas religions may serve a benign purpose by letting many people feel comfortable with the level of morality they themselves can attain, no religion holds its members to the high standards of moral responsibility that the secular world of science and medicine does! And I'm not just talking about the standards 'at the top' — among the surgeons and doctors who make life or death decisions every day. I'm talking about the standards of conscientiousness endorsed by the lab technicians and meal preparers, too. This tradition puts its faith in the unlimited application of reason and empirical inquiry, checking and re-checking, and getting in the habit of asking "What if I'm wrong?" Appeals to faith or membership are never tolerated. Imagine the reception a scientist would get if he tried to suggest that others couldn't replicate his results because they just didn't share the faith of the people in his lab! And, to return to my main point, it is the goodness of this tradition of reason and open inquiry that I thank for my being alive today.

From what can "ought" be derived. The most compelling answer is this: ethics must be somehow based on an appreciation of human nature — on a sense of what a human being is or might be, and on what a human being might want to have or want to be. If that is naturalism, then naturalism is no fallacy. No one could seriously deny that ethics is responsive to such facts about human nature. We may just disagree about where to look for the most compelling facts about human nature -n novels, in religious texts, in psychological experiments, in biological or anthropological investigations. The fallacy is not naturalism but, rather, any simple-minded attempt to rush from facts to values. In other words, the fallacy is greedy reductionism of values to facts, rather than reductionism considered more circumspectly, as the attempt to unify our world-view so that out ethical principles don't clash irrationally with the way the world is.

The evidence of evolution pours in, not only from geology, paleontology, biogeography, and anatomy (Darwin's chief sources), but from molecular biology and every other branch of the life sciences. To put it bluntly but fairly, anyone today who doubts that the variety of life on this planet was produced by a process of evolution is simply ignorant — inexcusably ignorant, in a world where three out of four people have learned to read and write. Doubts about the power of Darwin's idea of natural selection to explain this evolutionary process are still intellectually respectable, however, although the burden of proof for such skepticism has become immense...

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In a Thumbnail Sketch here is [the Multiple Drafts theory of consciousness] so far: There is no single, definitive "stream of consciousness," because there is no central Headquarters, no Cartesian Theatre where "it all comes together" for the perusal of a Central Meaner. Instead of such a single stream (however wide), there are multiple channels in which specialist circuits try, in parallel pandemoniums, to do their various things, creating Multiple Drafts as they go. Most of these fragmentary drafts of "narrative" play short-lived roles in the modulation of current activity but some get promoted to further functional roles, in swift succession, by the activity of a virtual machine in the brain. The seriality of this machine (its "von Neumannesque" character) is not a "hard-wired" design feature, but rather the upshot of a succession of coalitions of these specialists. The basic specialists are part of our animal heritage. They were not developed to perform peculiarly human actions, such as reading and writing, but ducking, predator-avoiding, face-recognizing, grasping, throwing, berry-picking, and other essential tasks. They are often opportunistically enlisted in new roles, for which their talents may more or less suit them. The result is not bedlam only because the trends that are imposed on all this activity are themselves part of the design. Some of this design is innate, and is shared with other animals. But it is augmented, and sometimes even overwhelmed in importance, by microhabits of thought that are developed in the individual, partly idiosyncratic results of self-exploration and partly the predesigned gifts of culture. Thousands of memes, mostly borne by language, but also by wordless "images" and other data structures, take up residence in an individual brain, shaping its tendencies and thereby turning it into a mind.

It is not "scientism" to concede the objectivity and precision of good science, any more than it is history worship to concede that Napoleon did once rule in France and the Holocaust actually happened. Those who fear the facts will forever try to discredit the fact-finders.

In fact, of course, science is an unparalleled playground of the imagination, populated by unlikely characters with wonderful names (messenger RNA, black holes, quarks) and capable of performing the most amazing deeds: sub-atomic whirling dervishes that can be in several places — everywhere and nowhere — at the same time; molecular hoop-snakes biting their own tails; self-copying spiral staircases bearing coded instructions; miniature keys searching for the locks in which they fit, on floating odysseys in a trillion synaptic gulfs.