Man knows and his capacity to know depends on his biological integrity; furthermore, he knows that he knows. As a basic psychological and, hence, bio… - Humberto Maturana

The relations that define a system as a unity, and determine the dynamics of interaction and transformations which it may undergo as such a unity constitute the organization of the machine.

[T]he space defined by an autopoietic system is self-contained and cannot be described by using dimensions that define another space. When we refer to our interactions with a concrete autopoietic system, however, we project this system on the space of our manipulations and make a description of this projection.

By autopoietic organization, Maturana and Varela meant the] processes interlaced in the specific form of a network of productions of components which realizing the network that produced them constitutes it as a unity.