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" "As hormonal amplification is the hallmark of all of the brain-to-gland relationships of neuroendocrinology, hormonal deamplification is the hallmark of all gland-to-brain relationships of endocrine neurology. This is the fundamental difference between the two sciences.
Richard M. Bergland (1932 - 2007) was an author, administrator, neurosurgeon and neuroscientist. He was chief of neurosurgery at Beth Israel Hospital of New York. He was also a Van Wagenen Scholar, a Markle Scholar and Macy Faculty Scholar and served academic appointments at Oxford, Harvard, Cornell and Columbia, among others.
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The brain has all the characteristics of a gland except one—leaky capillaries—the sturdy brain capillaries are collectively called the 'blood-brain-barrier'. This barrier can easily be demonstrated by injecting a blue dye into an animal; every other organ (except the testicle) turns blue, but the blood-brain barrier keeps the brain as white as snow.
Somehow the same nurses, physicians, administrators and legal ombudsmen who prevented the study of the ventricular fluid of a patient with senile dementia, or obesity, or depression, or schizophrenia, because of the risks, will encourage diagnostic tests and therapy for patients with epilepsy that are far more destructive and immutable than the measurement and manipulation of hormones in the ventricle.