[H]uman nature as encoded in our DNA isn't immutable. Mankind's barbaric track-record to date is an unreliable guide to the future. If Homo sapiens' … - David Pearce

More controversially, technology can accelerate the transition from harming to helping free-living sentient beings: mankind's fitfully expanding "circle of compassion". The civilising process needn't be species-specific but instead extend to free-living dwellers in tomorrow's wildlife parks. Every cubic metre of the biosphere will soon be computationally accessible to surveillance, micro-management and control. Fertility regulation via immunocontraception can replace Darwinian ecosystems governed by starvation and predation. Any species of obligate carnivore we choose to preserve can be genetically and behaviourally tweaked into harmlessness. Asphyxiation, disembowelling, and agonies of being eaten alive can pass into the dustbin of history.

All that matters is the pleasure-pain axis. Pain and pleasure disclose the world's inbuilt metric of (dis)value. Our overriding ethical obligation is to minimise suffering. After we have reprogrammed the biosphere to wipe out experience below "hedonic zero", we should build a "triple S" civilisation based on gradients of superhuman bliss. The nature of ultimate reality baffles me. But intelligent moral agents will need to understand the multiverse if we are to grasp the nature and scope of our wider cosmological responsibilities. My working assumption is non-materialist physicalism. Formally, the world is completely described by the equation(s) of physics, presumably a relativistic analogue of the universal Schrödinger equation. Tentatively, I'm a wavefunction monist who believes we are patterns of qualia in a high-dimensional complex Hilbert space. Experience discloses the intrinsic nature of the physical: the "fire" in the equations. The solutions to the equations of QFT or its generalisation yield the values of qualia. What makes biological minds distinctive, in my view, isn't subjective experience per se, but rather non-psychotic binding. Phenomenal binding is what consciousness is evolutionarily "for". Without the superposition principle of QM, our minds wouldn't be able to simulate fitness-relevant patterns in the local environment. When awake, we are quantum minds running subjectively classical world-simulations. I am an inferential realist about perception. Metaphysically, I explore a zero ontology [...] the total information content of reality must be zero on pain of a miraculous creation of information ex nihilo. Epistemologically, I incline to a radical scepticism that would be sterile to articulate. Alas, the history of philosophy twinned with the principle of mediocrity suggests I burble as much nonsense as everyone else.

[O]ne might naively suppose that a negative utilitarian would welcome human extinction. But only (trans)humans - or our potential superintelligent successors - are technically capable of phasing out the cruelties of the rest of the living world on Earth. And only (trans)humans - or rather our potential superintelligent successors - are technically capable of assuming stewardship of our entire Hubble volume.