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" "There are already people who are world class in India, for example C.N.R. Rao (who has worked mainly in solid-state and structural chemistry). He is an example of how you can do first rate international work within India. So I would say to Indians — you have it within you to do this (in India).
Venkatraman "Venki" Ramakrishnan (born 1952), an Indian-born American and British citizen, is a molecular biologist. He is the recipient of the 2009 Nobel Prize in Chemistry along with Thomas A. Steitz and Ada E. Yonath, "for studies of the structure and function of the ribosome”. He currently works at the MRC Laboratory of Molecular Biology in Cambridge, England. He has been honoured with the second highest civilian award of India, the Padma Vibhushan in 2010. The United Kingdom honoured him with Knighthood in 2012.
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It takes a certain amount of courage to tackle very hard problems in science, I now realise. You don't know what the timescale of your work will be: decades or only a few years. Or your approach may be fatally flawed and doomed to fail. Or you could get scooped just as you are finalising your work. It is very stressful.