There is but one truly serious philosophical problem, and that is suicide. Judging whether life is or is not worth living amounts to answering the fu… - William Styron

The good writing of any age has always been the product of someone's neurosis, and we'd have mighty dull literature if all the writers that came along were a happy bunch of chuckleheads.

"date of the award approached, I would not have accepted at all.
Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self — to the mediating intellect — as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode, although the gloom, "the blues" which people go through occasionally and associate with the general hassle of everyday existence are of such prevalence that they do give many individuals a hint of the illness in its catastrophic form."

I bought a bottle of old Grand-Dad bourbon; it was, I remember precisely, a full half pint, which was a prodigious amount of booze for a young man of twenty - at least, I know, for me. I got gloriously drunk on the Southern Railway local that rattled its way all night up through the Carolinas, gazing out at the bleak, moon-drenched wintry fields and happily pondered my deliverance. The chancellor, bless his soul, had really taken most of the curse off the bitter defeat I had initially felt there at the Biltmore. It really was better for me not to go to Oxford, I told myself, throwing in various Anglophilic injunctions: the food you wouldn't feed to a starving hound dog, the men were prancing homosexuals, the women all had foul breath, it was a moribund civilisation. "Screw Oxford," I remember saying aloud, and "Up yours, Cecil Rhodes!" Next year, instead of shivering to death in some library carrel, instead of - "Get this, old fellow!" I heard myself cackling - instead of writing a paper on the hexameters of Arthur Hugh Clough, that old Victorian nanny, I would be in New York, beginning my first novel.