The advent of small, inexpensive computers with superb graphics has changed the way many sciences are practiced, and the way that all sciences presen… - John Barrow

The secret of how galaxies came into being may well be fathomed by the study of the most elementary particles of matter in particle detectors buried deep underground; the identity of those elementary particles may be revealed by observations of distant starlight. ...by the coming together of the largest and the smallest aspects of the physical world our appreciation of the unity of the universe becomes more impressive and complete.

Einstein had spent the previous thirty years showing how we could understand the behaviour of whole universes with simple maths. Gamow saw that those universes must have had a past that was unimaginably different to the present. What had stopped them both in their tracks was Gamow's suggestion that the laws of physics could describe something being created out of nothing.

Ultimate explanation no longer means only a story that encompasses everything.