The scientific conception of chance is that of a measure based on experience; a knowledge of the average results of many events is used to replace ig… - Karl Pearson

That this change of view as to the basis of science cannot take place without misunderstanding, or without giving an opportunity to those who dislike science to decry its weaknesses, is only natural. To change the basis of operations during a campaign always gives a chance to the enemy, but the chance must be risked if thereby we place ourselves permanently in a position of greater strength...

Professor Huxley has invented the term Agnostic... for those who limit the possibility of knowledge in certain fields. ...Professor E. du Bois-Reymond has raised the cry "Ignorabimus" ("We shall be ignorant") and... undertaken the difficult task of demonstrating that with regard to certain problems human knowledge is impossible. ...Now ...there is great danger in this cry. ...[T]he attempt to demonstrate an endless futurity of ignorance ...approaches despair. ...Evolution has taught us of the continual growth of man's intellectual powers.

[T]he task of science can never end till man ceases to be, till history is no longer made, and development itself ceases.