Assuming the simulators, or at least the early generations of them, have a very advanced knowledge of the laws of Nature, it's likely that they would… - John Barrow

Even today, there persists... a feeling that the creation of the Universe out of nothing must violate some basic conservation law that stops one from getting something for nothing. Nevertheless, there is actually no evidence that the Universe as a whole possesses a non-zero value of any such conserved quantity. The total mass-energy of all the constituents of a finite Universe appears to be always equal in magnitude but opposite in sign to the total gravitational potential energies of those particles. ...Similarly, there is no evidence that the Universe possesses any overall net rotation or electric charge.

The spooky ether was persistent. It took an Einstein to remove it from the Universe. ...Gradually, over the last twenty years, the vacuum has turned out to be more unusual, more fluid, less empty, and less intangible than even Einstein could have imagined. Its presence is felt on the very smallest and largest dimensions over which the forces of Nature act.

The logic of the Greeks prevents them having the idea at all and it is to the Indian cultures that we must look to find thinkers who are comfortable with the idea that Nothing might be something.