Most accursed, wicked, barbarous, cruel, unnatural, unjust and diabolical.

Wit is cultured insolence.

It is because of the Biblical curse on man's search for knowledge, which has so paralyzed his mind during the past ages, and its detrimental effect upon progress, that makes the Bible the most wicked, the most detestable, the most pernicious, and the most obnoxious book ever published. ... We will never achieve intellectual liberty until the wickedness of this book has been discarded with the belief in the flatness of the earth.

Wit is educated insolence.

Wit is educated insolence.

Of all our infirmities, the most savage is to despise our being.

An intellectual hatred is the worst.

... the whole thing is disgraceful from beginning to end. Disgraceful and vulgar.

Without virtue, man is most unholy and savage, and worst in regard to sex and eating.

A little, wretched, despicable creature; a worm, a mere nothing, and less than nothing; a vile insect that has risen up in contempt against the majesty of Heaven and earth.

[T]he most repugnant bastard there is: the bastard-octopus.

These widows, sir, are the most perverse creatures in the world.

Sincerity is the most overrated virtue in the catalogue.

"Your stupidity is appalling!"
"Most stupidity is!"