There's no better guarantee of failure than convincing yourself that success is impossible... - Max Tegmark

Philosophy is written in this grand book, the universe, which stands continually open to our gaze. But the book cannot be understood unless one first learns to comprehend the language and read the characters in which it is written. It is written in the language of mathematics, and its characters are triangles, circles, and other geometric figures without which it is humanly impossible to understand a single word of it; without these one is wandering in a dark labyrinth. — Galileo Galilei, The Assayer, 1623

Real knowledge is to know the extent of one’s ignorance. — Confucius The highest form of ignorance is when you reject something you don’t know anything about. — Wayne Dyer

Some key physical entities such as empty space, elementary particles and the wavefunction appear to be purely mathematical int he sense that their only intrinsic properties are mathematical properties.