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" "During electroconvulsive therapy the blood-brain barrier is opened and during the time that it remains open there are heroically high levels of circulating pituitary hormones. Thus there is every reason to believe that... it delivers hormones to the brain...
Richard M. Bergland (1932 - 2007) was an author, administrator, neurosurgeon and neuroscientist. He was chief of neurosurgery at Beth Israel Hospital of New York. He was also a Van Wagenen Scholar, a Markle Scholar and Macy Faculty Scholar and served academic appointments at Oxford, Harvard, Cornell and Columbia, among others.
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The ventricles of the human brain... are filled with hormones, and until the hormones swimming in these oceans are dredged out, countless millions of our fellows will remain with brain illnesses that can be neither understood nor treated. Many of their hormone-hungry brains may be fixed as easily as hormone-hungry bodies are fixed with thyroid hormone, insulin, oestrogen and testosterone, but that work cannot begin until cause and effect relationships between brain hormones and brain diseases have been established.