Here is a list of some of the questions and their short answers (...) The interesting thing is to recognize how totally unavoidable they are, provide… - Alexander Rosenberg

Why is there anything at all? or as the question is famously put, Why is there something rather than nothing? Physics, especially quantum physics, shows that the correct answer to this question is: No reason, no reason at all.

Science can explain why we value things, but the same goes for values we reject as wrong. That's why scientific explanations of what we value cannot justify those values or serve as a basis to enforce them on others. Since science is the only possible source of justification, if it doesn't work to justify values, nothing does.

Scientism starts with the idea that the physical facts fix all the facts, including the biological ones. These in turn have to fix the human facts—the facts about us, our psychology, and our morality. After all, we are biological creatures, the result of a biological process that Darwin discovered but that the physical facts ordained. As we have just seen, the biological facts can't guarantee that our core morality (or any other one, for that matter) is the right, true, or correct one. If the biological facts can't do it, then nothing can. No moral code is right, correct, true. That's nihilism. And we have to accept it.