Twenty years from now, the disease, 'presenile dementia' will be understood as well as diabetes is today. - Richard Bergland

Scientists have mastered the techniques of hormone analysis, measurement and manufacture. What is lacking is the correlation between a specific brain disease and a specific brain hormone. …these correlations can only come from a medical team of co-operating physicians.

The science of neuroendocrinology—the brain-to-pituitary link that was discerned by [Joe] Hinsey, [George] Wislocki, du Vigneaud, and [Geoffrey] Harris—is dependent upon hormones flowing within nerve axons. This phenomenon, axonal flow, was first noted by Ernst and Barta Scharrer... For many decades it was assumed that axonal flow was always 'down'... away from the brain.

In decades to come ventricular catheterization performed to measure hormone concentrations will become as routine as the measurement of lumbar 'pressure' is today.