Perhaps the first lesson to be learned from biology is that there are lessons to be learned from biology. - Robert Rosen

Let us begin by observing that the word "system" is almost never used by itself; it is generally accompanied by an adjective or other modifier: physical system; biological system; social system; economic system; axiom system; religious system; and even "general" system. This usage suggests that, when confronted by a system of any kind, certain of its properties are to be subsumed under the adjective, and other properties are subsumed under the "system," while still others may depend essentially on both. The adjective describes what is special or particular; i.e., it refers to the specific "thinghood" of the system; the "system" describes those properties which are independent of this specific "thinghood."

The physical structures of organisms play only a minor and secondary role... The only requirement which physical structure must fulfill is that it allow the characteristic behaviors themselves to be manifested. Indeed, if this were not so, it would be impossible to understand how a class of systems as utterly diverse in physical structure as that which comprises biological organisms could be recognised as a unity at all.

For a long time, people have been trying to characterize or define the notion of system. After all, “systems” are supposed to be what System Theory is about. The results so far have been contradictory and unsatisfactory. This confusion at the foundations has led many to conclude that there is no such thing as a "system" and hence to deny that System Theory is about anything. Even those most sympathetic to the notion have difficulties at this level. The very founders of System Theory did not try to say what a system was; and as for System Theory, they characterized it only obliquely, by saying it comprised all studies of interest to more than one discipline. They thereby begged the entire question.