There is a good deal more to nothing than meets the eye. - John Barrow

Einstein had spent the previous thirty years showing how we could understand the behaviour of whole universes with simple maths. Gamow saw that those universes must have had a past that was unimaginably different to the present. What had stopped them both in their tracks was Gamow's suggestion that the laws of physics could describe something being created out of nothing.

We say that the string is 'random' if there is no other representation of the string which is shorter than itself. But we will say that it is 'non-random' if there does exist such an abbreviated representation. ...In general, the shorter the possible representation... the less random... On this view we recognize science to be the search for algorithmic compressions.

We have witnessed a revolution in the history of science. Not the sort of revolution that philosophers of science once believed in—they don't happen any more—but a revolution brought about by new tools, different ways of seeing, and novel ways of understanding. Nothing old needed to be overthrown to make way for the new.
The future of science will be increasingly dominated by artificial images and simulations.