It seems to me what is called for is an exquisite balance between two conflicting needs: the most skeptical scrutiny of all hypotheses that are served up to us and at the same time a great openness to new ideas. If you are only skeptical, then no new ideas make it through to you. You never learn anything new. You become a crotchety old person convinced that nonsense is ruling the world. (There is, of course, much data to support you.)
On the other hand, if you are open to the point of gullibility and have not an ounce of sceptical sense in you, then you cannot distinguish useful ideas from the worthless ones. If all ideas have equal validity then you are lost, because then, it seems to me, no ideas have any validity at all.

What is called for is an exquisite balance between two conflicting needs: the most skeptical scrutiny of all hypotheses that are served up to us and at the same time a great openness to new ideas. If you are only skeptical, then no new ideas make it through to you. On the other hand, if you are open to the point of gullibility and have not an ounce of skeptical sense in you, then you cannot distinguish useful ideas from the worthless ones.

It seems to me what is called for is an exquisite balance between two conflicting needs: the most skeptical scrutiny of all hypotheses that are served up to us and at the same time a great openness to new ideas...If you are only skeptical, then no new ideas make it through to you … On the other hand, if you are open to the point of gullibility and have not an ounce of skeptical sense in you, then you cannot distinguish the useful ideas from the worthless ones.

It seems to me what is called for is an exquisite balance between two conflicting needs: the most skeptical scrutiny of all hypotheses that are served up to us and at the same time a great openness to new ideas ... If you are only skeptical, then no new ideas make it through to you ... On the other hand, if you are open to the point of gullibility and have not an ounce of skeptical sense in you, then you cannot distinguish the useful ideas from the worthless ones.'''

If you’re only sceptical, then no new ideas make it through to you. You never learn anything. You become a crochety misanthrope convinced that nonsense is ruling the world. (There is, of course, much data to support you.) Since major discoveries in the borderlines of science are rare, experience will tend to confirm your grumpiness. But every now and then a new idea turns out to be on the mark, valid and wonderful. If you’re too resolutely and uncompromisingly sceptical, you’re going to miss (or resent) the transforming discoveries in science, and either way you will be obstructing understanding and progress. Mere scepticism is not enough.

What skeptical thinking boils down to is the means to construct, and to understand, a reasoned argument and — especially important — to recognize a fallacious or fraudulent argument. The question is not whether we like the conclusion that emerges out of a train of reasoning, but whether the conclusion follow from the premise or starting point and whether that premise is true,

At the heart of science is an essential balance between two seemingly contradictory attitudes - an openness to new ideas, no matter how bizarre or counterintuitive, and the most ruthlessly skeptical scrutiny of all ideas, old and new. This is how deep truths are winnowed from deep nonsense. The collective enterprise of creative thinking and skeptical thinking, working together, keeps the field on track. Those two seemingly contradictory attitudes are, though, in some tension.

I think skepticism is an antidote for nonsense –and there's always nonsense in life– and also it's the method for discovering what's true or false. And yes, we should use it throughout life.

The business of scepticism is to be dangerous. Scepticism challenges established institutions. If we teach everybody, including, say, high school students, habits of sceptical thought, they will probably not restrict their scepticism to UFOs, aspirin commercials and 35,000-year-old channellees. Maybe they’ll start asking awkward questions about economic, or social, or political, or religious institutions. Perhaps they’ll challenge the opinions of those in power. Then where would we be?

The scientific skepticism of our age professes to spring from a sense of the extreme fallaciousness of the human senses, and the liability besetting us all to deceive ourselves into a belief which gratifies the faculty of wonder. It is held as a rare and valuable gift to be able to observe a fact correctly. We are pathetically told that what a man thinks he saw, is often a mere hypothesis of his imagination as to what he saw, and may be wholly wrong.

Skepticism is part of reflection... In religion and ethics, in politics, you have to be skeptical of claims that people make. It applies to all parts of life. Your own beliefs and the beliefs of others, and your willingness to examine these, to see if they hold up under scrutiny.

But our openness to the dazzling possibilities presented by modern science must be tempered by some hard-nosed skepticism. Many interesting possibilities simply turn out to be wrong. An openness to new possibilities and a willingness to ask hard questions are both required to advance our knowledge. And the asking of tough questions has an ancillary benefit: political and religious life in America, especially in the last decade and a half, has been marked by an excessive public credulity, an unwillingness to ask difficult questions, which has produced a demonstrable impairment in our national health. Consumer skepticism makes quality products. This may be why governments and churches and school systems do not exhibit unseemly zeal in encouraging critical thought. They know they themselves are vulnerable.

A skepticism concerning what one beholds - whether in the arts, in the sciences, or in the deeply etched channels of fashionable response - contains a force essential to the survival of civilized man.

If there are any lessons to be learned from history, it is that we should be skeptical of all points of view, including those of the skeptics. No one is infallible, and no one can claim a monopoly on truth or virtue. It would be contradictory for skepticism to seek to translate itself into a new faith. One must view with caution the promises of any new secular priest who might emerge promising a brave new world—if only his path to clarity and truth is followed. Perhaps the best we can hope for is to temper the intemperate and to tame the perverse temptation that lurks within.