Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self — to the mediating intellect — as to ve… - William Styron

What I had begun to discover is that, mysteriously and in ways that are totally remote from normal experience, the grey drizzle of horror induced by depression takes on the quality of physical pain. But it is not an immediately identifiable pain, like that of a broken limb. It may be more accurate to say that despair, owing to some evil trick played upon the sick brain by the inhabiting psyche, comes to resemble the diabolical discomfort of being imprisoned in a fiercely overheated room. And because no breeze stirs this cauldron, because there is no escape from the smothering confinement, it is natural that the victim begins to think ceaselessly of oblivion

I raise my eyes upward. There alone amidst the blue, steadfast, unmoving, fiery marvel of brightness, shines the morning star. Never has that star seemed so radiant, and I stand gazing at it and do not move though the chill of the damp floor imprisons my feet in piercing icebound pain. Surely I come quickly …

And as I began to discipline and harness myself, began for the first time to examine as coldly and as clinically as I could the tough problems which before this I had refused to face, I had a fine revelation. I realized that what had been lacking in my novelist's vision was really a sense of architecture - a symmetry, perhaps unobtrusive but always there, without which a novel sprawls, becoming a self-indulgent octopus. It was a matter of form, and up until now this was an issue that out of laziness or fear, perhaps both, I had tried to avoid.
I completed Lie Down in Darkness on a spring evening in 1951 in a room on West Eighty-Eighth Street in Manhattan.