It is easy to romanticise, say, tigers or lions and cats. We admire their magnificent beauty, strength and agility. But we would regard their notiona… - David Pearce

I argue that what breathes fire into the QM equations is field-theoretic what-it's-likeness: "microqualia" to use a philosopher's term of art. The different values of the solutions to the ultimate physical equations exhaustively yield the abundance of different values of subjectivity. There is no room for dualism; "nomological danglers"; causally inert epiphenomena; classical, porridge-like lumps of otherwise insentient but magically mind-secreting matter, etc. There is no "explanatory gap" because there aren't any material objects - not even brains or nerve cells as commonly (mis)perceived. Instead, over millions of years, non-equilibrium thermodynamics and universal, (neo-)Darwinian principles of natural selection have contrived to organise a minimal and self-intimating subjective sludge of microqualia into complex functional living units. Initially, these units have taken the form of self-replicating, information-bearing biomolecular patterns. Eventually, selection-pressure has given rise to complex minds as well, albeit as just one part of the throwaway host vehicles by which our genes leave copies of themselves. Conscious mind, on this proposal, is a triumph of organisation: our egocentric virtual worlds are warm and gappy QM-coherent states of consciousness. Contra materialist metaphysics, sentience of any kind is not the daily re-enactment of an ontological miracle. Moreover the idea that what-it's-like-ness is the fire in the equations is (at least) consistent with orthodox relativistic quantum field theory - because the theorists' key notions (e.g. that of a field, string, brane, etc) are defined purely mathematically. In other cases, they readily lend themselves to such a reconstruction. Using the word "physical" doesn't add anything of substance.

Humans already massively intervene in Nature, whether through habitat destruction, captive breeding programs for big cats, "rewilding", etc. So the question is not whether humans should "interfere", but rather what ethical principles should govern our interventions.

[H]uman nature as encoded in our DNA isn't immutable. Mankind's barbaric track-record to date is an unreliable guide to the future. If Homo sapiens' nastier alleles and their more sinister combinations can be silenced or edited out of the genome, and new improved code-sequences inserted instead, then the pessimists will be confounded. A major discontinuity in the development of life lies ahead. Providentially, we've learned that the DNA-driven world isn't written in God-given proprietary code it would be hubris to tamper with, but in bug-ridden open source amenable to improvement.