We can see, now, that the social background of the Empire makes wars of conquest impossible for it. Under weak Emperors, it is torn apart by generals… - Isaac Asimov

You see, proteins, as I probably needn't tell you, are immensely complicated groupings of amino acids and certain other specialized compounds, arranged in intricate three-dimensional patterns that are as unstable as sunbeams on a cloudy day. It is this instability that is life, since it is forever changing its position in an effort to maintain its identity — in the manner of a long rod balanced on an acrobat's nose.

If there is a misuse of power, it is on her part. My crime is that I have never labored to make myself popular — I admit that much — and I have paid too little attention to fools who are old enough to be senile but young enough to have power.

If you're born in a cubicle and grow up in a corridor, and work in a cell, and vacation in a crowded sun-room, then coming up into the open with nothing but sky over you might just give you a nervous breakdown.