Work on Stuff that Matters - Tim O'Reilly

Collective intelligence. Think of how Wikipedia works, how Amazon harnesses user annotation on its site, the way photo-sharing sites like Flickr are bleeding out into other applications... We're entering an era in which software learns from its users and all of the users are connected.

Just do something that lights you up, and lights up your customers, and lights up the world and scale to that.

Healthcare is one of the areas where open data will potentially take off soonest and have the biggest impact.