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"Neglect - even misstatement - of recent scientific data was also evident in last year's testimony before this subcommittee by the Christopher Reeve Paralysis Foundation. Mr. Reeve, on behalf of the Foundation, testified that adult stem cells are no substitute for embryonic cells because they cannot be "pluripotent" but are confined to a narrow range of specialization. Yet a few weeks after that hearing, researchers funded by the NIH and the Christopher Reeve Paralysis Foundation published a study indicating that adult bone marrow stem cells "may constitute an abundant and accessible cellular reservoir for the treatment of a variety of neurologic diseases." The first sentence of the published study states: "Pluripotent stem cells have been detected in multiple tissues in the adult, participating in normal replacement and repair, while undergoing self-renewal. The authors cite eleven other studies in support of this observation. Their article, prepared under the aegis of Mr. Reeve's foundation, was received for publication in March 2000, before Mr. Reeve testified in April that adult stem cells cannot be pluripotent.
Christopher D'Olier Reeve (25 September 1952 – 10 October 2004) was an American actor, director, producer, writer, lobbyist, and husband of actress Dana Reeve. He is most famous for playing the role of Superman in the film Superman (1978) and its three sequels.
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I've always been a practical person, not one to waste time pursuing unrealistic goals or dreams. But today's dreams can soon become tomorrow's reality in biomedical research. Scientists studying how the brain's cells and chemicals develop, interact, and communicate with the rest of the body have been making strides in alleviating the suffering of patients with Alzheimer's, strokes, Parkinson's, and MS, as well as brain and spinal cord injuries. Only recently researchers have dis-covered that stem cells, which have the ability to adapt to any environmentt in the body, will probably be the most important factor in curing all of these conditions. For example, in order to repair the damaged spinal cord, stem cells can be extracted from the ventricles of the brain or from bone marrow and genetically engineered to become nerve tissue. Highly successful experiments on mice have shown that when these transformed stem cells are transferred into the site of the injury, they apparently understand that their mission is to replace the damaged circuitry, which causes significant functional recovery. Mice that have had their spinal cords completely transected have been able to walk confidently across tightropes and climb rope ladders after this treatment. You would think that these breakthroughs would be a cause for celebration throughout the disabled community. In scientific terms, we are very close to achieving the impossible; in practical terms, we have a long way to go. But it is very disheartening to hear a leading researcher announce, "give us a hundred million dollars and we can cure Parkinson's"; or, "if we raise 300 million dollars, we can find a cure for paralysis in 5 years instead of 15." The idea of spending 15 more years in a wheelchair being fed, dressed, and washed by others would be tolerable if the scientists were still in the dark and there was no hope of recovery. I think most disabled people would agree with me that it is very difficult to cope psychologically with the stark reality that our future now depends mostly on money.
I need to object, and that is that, Senator, you insist on separating therapeutic cloning and embryonic stem cells. However, in my own case, I require re-myelination of nerves. That means replacing the conductive coat of fat, myelin, that allows electricity to come down, currents from the brain to the central nervous system for function. At the moment, only embryonic stem cells have the potential to do that, and experiments are being done now in larger animals demonstrating that.