[N]ever in the history of science have we been given such a gift of being able to use cells that can become any tissue or cell type in the body for the purpose of healing. I think that if you do not have the combination of therapeutic cloning and embryonic stem cells, you are going to be condemning a lot of people to unnecessary and death. If I look around at what else is going on, for years just in the spinal cord community, there has been research on growth factors and Schwann cells, and there have been efforts to stop protein inhibitor, but they have not yet shown the same promise that the embryonic stem cells do, and at the moment, in two places, Washington University in St. Louis and the University of California at Irvine, researchers have been conducting very successful experiments using human embryonic stem cells in animal models in both the acute and chronic phases and getting recovery. Of course, they are going to have to move to the higher animal forms before humans, but the promise is absolutely extraordinary, and I cannot think of any other kind of therapy that would be as effective and as promising as this is. And when I read articles or hear people say that the promise of human embryonic stem cells is dubious, I am very disturbed, because the only reason they get to say that is because the NIH has not been allowed to spend a single dollar on embryonic stem cell research. They have a budget now of $25 billion, and yet, because of lack of guidelines and because of the restrictions that have been imposed on the NIH so far, not one human embryonic stem cell project has been federally funded. That is why you are seeing such slow progress. And if we continue that way, I am going to be in this wheelchair for a long time that I do not need to be, and others like me.
American actor (1952–2004)
Christopher D'Olier Reeve (25 September 1952 – 10 October 2004) was an American actor, director, producer, writer, lobbyist, and husband of actress Dana Reeve. He is most famous for playing the role of Superman in the film Superman (1978) and its three sequels.
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Birth Name:
Christopher D'Olier Reeve
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Superman is nothing more than a popular retelling of the Christ story, or Greek mythology. It's an archetype, watered down and made in vivid colors for twelve-year-old's mentality. It's pop mythology, which extends to the actor, then seeps over to a demand that that actor reflect the needs of the worshipers. The worship doesn't only go on in the temples — it goes on in the streets, and restaurants, in magazines. But, you know, I'm from New Jersey, I'm not from Olympus or Krypton, so back off 'cause I can't take the responsibility.
I have to stop this cascade of memories, or at least take them out of their drawer only for a moment, have a brief look, and put them back. I know how to do it now: I have to take the key to acting and apply it to my life. There is no other way to survive except to be in the moment. Just as my accident and its aftermath caused me to redefine what a hero, I've had to take a hard look at what it means to live as fully as possible in the present. How do you survive in the moment when it's bleak and painful and the past seems so seductive?
Today, human trials to defeat Parkinson's are underway in Sweden. In Israel, macrophages, scavenger cells that eat debris in the body, are being used to repair the damaged spinal cord within 2 weeks of injury. The first human subject was a 19-year-old girl from Colorado. Last week, the House of Lords in the United Kingdom passed legislation permitting research on cloned human embryos for the second time. Those are not rogue nations behaving irresponsibly. They are allies, no less moral than we are.
I work with Dr. John McDonald at Washington University in St. Louis, and he is a very knowledgeable researcher on (Inaudible) stem cells, and a few years ago he said to me that in order to cure my particular condition, which is demyelination of nerves in a very small area of the spinal cord, right at the second cervical vertebrae, that if you imagine the rubber coating around a wire that allows conductivity of electricity, the same thing as with nerves, myelin is like that rubber coating. It's a fatty substance that if it comes off of the nerves, then signals do not go from the brain down to the spinal cord as required. However, it is possible, and he's demonstrated this as graphic(?) as possible, to re-myelinate. Now, a few years ago, he said, we would be willing to inject human embryonic stem cells into you and hope for the best. But hoping for the best is a very dangerous proposition for people with spinal cord injuries because our spinal cord injury affects every organ in the body, and the most serious side effect is that it severely compromises the immune system, so spinal cords patients, particularly with high level injuries like mine, are prone first to pneumonia, which I've had at least five times since my injury, many patients often die from that. Also, it compromises the cardiovascular system, compromises the digestive tract, the ... your whole bowel-bladder-sexual function, skin integrity and also bone density, so that osteoporosis becomes a very ... a very critical factor. So literally he said to me that the immunosuppression that would be required just to inject 30million human embryonic stem cells from an anonymous donor might kill me. And now, he would be unwilling as a doctor, because of the ethics involved that a doctor is ethically bound to give his patients the best possible treatment, he would not inject me with embryonic stemcells unless we go the other route, which is therapeutic cloning- taking an egg, removing the nucleus, taking DNA from my skin and deriving stem cells from that, which would be injected in a manner that would probably not be rejected by my immune system. So my future, and others would agree, many scientists would agree, my future, in terms of being able to recover will depend on some way of delivering stem cells without compromising my immune system and therapeutic cloning, which would use my DNA is the best hope.
I believe, throughout history, there has been common agreement in societies around the world that the life results because of the union of male and female. Whether it's done in a test tube, or whether it's done through intercourse. And fertilized embryos in clinics are still the union, result of the union of male and female. Therapeutic cloning takes an egg that is not fertilized, and is left in the cellular stage, in the very early stages, about three to five, seven days, then the nucleus is removed and the DNA from a patient. Either male or female can be put into it. Now, that is an aberrant life form. If you were to take it further and implant it, then only insane people would want to do that, in my opinion. But considering the fact that they're talking ... you're talking about the difference of life as we've understood it for hundreds of thousands of years, versus a collection of cells that will never become a human being, and I don't even believe deserves a status of the word embryo. It could be called a pseudo-embryo, it could be called, you know, some other name should come up from it, because just like test tube babies scared people before, the buzzword embryo scares people today. Cloning scares people today, but this is simply a manipulation of cells that are not equivalent to life as we've always known it.
Today, 100 million Americans suffer from serious or currently incurable diseases. Fifty-four million Americans are disabled. Our Government is supposed to do the greatest good for the greatest number of people. Beyond that, we have a moral responsibility to help others. Time is absolutely critical. If the Government forces scientists' attempt to make adult stem cells behave like embryonic stem cells, they might waste 5 years or more and fail. In the meantime, hundreds of thousands will have died. Why do we need therapeutic cloning? As a layman, several important reasons come to mind. One, implantation of human embryonic stem cells is not safe unless they contain the patient's own DNA. Two, efforts, to repair central nervous system disorders may need to recapitulate the process of fetal development, and that could only be accomplished by human embryonic stem cells. Three, therapeutic cloning is done without fertilizing an egg. It can be strictly regulated. If we also enforce an absolute ban on reproductive cloning, we will not slide down the dreaded slippery slope into moral and ethical chaos. Any powerful new technology comes with the possibility for abuse. But when we decide that the benefit to society is worth the risk, we take every possible precaution and go forward. The unfertilized eggs that will be used for nucleus transplantation will never leave the laboratory and will never be implanted in a womb. But if we do not make this research legal, if we do not use Government funding and oversight, it will happen privately, dangerous, unregulated and uncontrolled. And our country is about to lose its preeminence in science and medicine. We took a giant step backward in the 1970's when the NIH was not allowed to fund its in vitro research until an advisory commission could be formed to consider the issue. In the meantime, there was rapid progress in England, and the first test tube baby was born in 1978. For purely political reasons, we did not succeed and so far, 177,000 children have been conceived in 400 facilities around the country.