[W]hile the budget for research is negotiated annually on Capitol Hill, Alzheimer's has crippled 4 million Americans. This disease alone costs our nation 100 billion dollars every year and this number is expected to rise dramatically as baby boomers continue to age. Parkinson's afflicts nearly half a million Americans and costs us at least 6 million a year. Another half million Americans suffer strokes each year, costing more than 30 million in medical treatment, rehabilitation, and long-term care. Diabetes afflicts nearly 16 million people. It is the leading cause of blindness, kidney disease, and limb amputations; and it costs our nation between 90 and 140 billion dollars a year.
American actor (1952–2004)
Christopher D'Olier Reeve (25 September 1952 – 10 October 2004) was an American actor, director, producer, writer, lobbyist, and husband of actress Dana Reeve. He is most famous for playing the role of Superman in the film Superman (1978) and its three sequels.
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Birth Name:
Christopher D'Olier Reeve
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Superman is nothing more than a popular retelling of the Christ story, or Greek mythology. It's an archetype, watered down and made in vivid colors for twelve-year-old's mentality. It's pop mythology, which extends to the actor, then seeps over to a demand that that actor reflect the needs of the worshipers. The worship doesn't only go on in the temples — it goes on in the streets, and restaurants, in magazines. But, you know, I'm from New Jersey, I'm not from Olympus or Krypton, so back off 'cause I can't take the responsibility.
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I work with Dr. John McDonald at Washington University in St. Louis, and he is a very knowledgeable researcher on (Inaudible) stem cells, and a few years ago he said to me that in order to cure my particular condition, which is demyelination of nerves in a very small area of the spinal cord, right at the second cervical vertebrae, that if you imagine the rubber coating around a wire that allows conductivity of electricity, the same thing as with nerves, myelin is like that rubber coating. It's a fatty substance that if it comes off of the nerves, then signals do not go from the brain down to the spinal cord as required. However, it is possible, and he's demonstrated this as graphic(?) as possible, to re-myelinate. Now, a few years ago, he said, we would be willing to inject human embryonic stem cells into you and hope for the best. But hoping for the best is a very dangerous proposition for people with spinal cord injuries because our spinal cord injury affects every organ in the body, and the most serious side effect is that it severely compromises the immune system, so spinal cords patients, particularly with high level injuries like mine, are prone first to pneumonia, which I've had at least five times since my injury, many patients often die from that. Also, it compromises the cardiovascular system, compromises the digestive tract, the ... your whole bowel-bladder-sexual function, skin integrity and also bone density, so that osteoporosis becomes a very ... a very critical factor. So literally he said to me that the immunosuppression that would be required just to inject 30million human embryonic stem cells from an anonymous donor might kill me. And now, he would be unwilling as a doctor, because of the ethics involved that a doctor is ethically bound to give his patients the best possible treatment, he would not inject me with embryonic stemcells unless we go the other route, which is therapeutic cloning- taking an egg, removing the nucleus, taking DNA from my skin and deriving stem cells from that, which would be injected in a manner that would probably not be rejected by my immune system. So my future, and others would agree, many scientists would agree, my future, in terms of being able to recover will depend on some way of delivering stem cells without compromising my immune system and therapeutic cloning, which would use my DNA is the best hope.
The prosperity that we've enjoyed in the 90's has spawned a new breed of individuals who have amassed tremendous fortunes at a very young age. Many of them have reaped the rewards of a stock market that seems to have no upper limit. Others have moved swiftly into the fast lane of the information superhighway, and achieved a net worth in the billions long before their 40th birthday. Often they literally don't know what to do with that much money. Unfortunately, philanthropy is not something many of them perceive as an important responsibility of the wealthy. While of course there are a number of notable exceptions, too many of these young billionaires become obsessed with privacy and are more likely to build half a dozen homes in different parts of the world than to give back to society. In the early years of this century, the notion of what it meant to be a "gentleman" informed the actions of the very rich - the Vanderbilts, Astors, Rockefellers, Carnegies, and the like. They too built "cottages" in Newport, and enjoyed their yachts. But they also created foundations, endowed universities, built hospitals and libraries, and donated land for public use. I don't think it's a wild stretch of the imagination to believe that if they knew that 300 million dollars would cure paralysis in 5 years instead of 15, they would have reached for their checkbooks. But we must not wallow in nostalgia for the Gilded Age, when in fact, there is so much potential in the present. Ten corporations could each give 30 million dollars without any undue hardship. When people ask me what are my hopes and dreams for the new Millennium, my answer is I hope technology will not diminish genuine human contact and compassion. I still believe that when people really make the effort to understand each other, the possibilities are limitless. The solutions to the problems we will face in the 21st century --- such as overpopulation, the environment, education, and disease --- will only be achieved by every one of us doing our part. We must appeal to the government, the private sector, venture capitalists, corporations of all sizes, and every individual who can only afford to give 5 dollars to help further the cause. You in the media can lead the way by creating awareness and affecting public opinion. In the last hundred years, we invented the automobile, the airplane, and weapons of mass destruction. We journeyed to the moon and built shiny new cities throughout the country. We concerned ourselves with material success, convenience, and a higher standard of living. Now it's time for America to take care of its own. The life expectancy for Americans has practically doubled over the course of this century. Now it is our responsibility to ensure that from cradle to grave, these years are ones of quality and productivity, not pain and suffering. The time is now, at the dawn of a new Millennium.
When I met with the President in May of 1996, he stated that the ratio of research to clinical results is greater in this country than anywhere else in the world. Money spent on research brings practical results that absolutely justify the investment. Let's look at a few examples. NIH-sponsored research has resulted in the identification of genetic mutations that cause osteoporosis, Lou Gehrig's Disease, cystic fibrosis and Huntington's disease. Effective treatment for Acute Lymphoblastic Leukemia (ALL) has been developed and today nearly 80 percent of children diagnosed with ALL are alive and disease-free after 5 years. Because of research, the nature of medicine is changing. We are approaching disease at the cellular level. We are targeting problems earlier, more specifically, less intrusively, with greater success and fewer side effects. Advances in genetics will soon let us intervene in disease before symptoms appear.
When the first Superman movie came out, I gave dozens of interviews to promote it. The most frequent question was: What is a hero? My answer was that a hero is someone who commits a courageous action without considering the consequences. Now my definition is completely different. I think a hero is an ordinary individual who finds the strength to persevere and endure in spite of overwhelming obstacles. They are the real heroes, and so are the families and friends who have stood by them.
Today, 100 million Americans suffer from serious or currently incurable diseases. Fifty-four million Americans are disabled. Our Government is supposed to do the greatest good for the greatest number of people. Beyond that, we have a moral responsibility to help others. Time is absolutely critical. If the Government forces scientists' attempt to make adult stem cells behave like embryonic stem cells, they might waste 5 years or more and fail. In the meantime, hundreds of thousands will have died. Why do we need therapeutic cloning? As a layman, several important reasons come to mind. One, implantation of human embryonic stem cells is not safe unless they contain the patient's own DNA. Two, efforts, to repair central nervous system disorders may need to recapitulate the process of fetal development, and that could only be accomplished by human embryonic stem cells. Three, therapeutic cloning is done without fertilizing an egg. It can be strictly regulated. If we also enforce an absolute ban on reproductive cloning, we will not slide down the dreaded slippery slope into moral and ethical chaos. Any powerful new technology comes with the possibility for abuse. But when we decide that the benefit to society is worth the risk, we take every possible precaution and go forward. The unfertilized eggs that will be used for nucleus transplantation will never leave the laboratory and will never be implanted in a womb. But if we do not make this research legal, if we do not use Government funding and oversight, it will happen privately, dangerous, unregulated and uncontrolled. And our country is about to lose its preeminence in science and medicine. We took a giant step backward in the 1970's when the NIH was not allowed to fund its in vitro research until an advisory commission could be formed to consider the issue. In the meantime, there was rapid progress in England, and the first test tube baby was born in 1978. For purely political reasons, we did not succeed and so far, 177,000 children have been conceived in 400 facilities around the country.
I believe, throughout history, there has been common agreement in societies around the world that the life results because of the union of male and female. Whether it's done in a test tube, or whether it's done through intercourse. And fertilized embryos in clinics are still the union, result of the union of male and female. Therapeutic cloning takes an egg that is not fertilized, and is left in the cellular stage, in the very early stages, about three to five, seven days, then the nucleus is removed and the DNA from a patient. Either male or female can be put into it. Now, that is an aberrant life form. If you were to take it further and implant it, then only insane people would want to do that, in my opinion. But considering the fact that they're talking ... you're talking about the difference of life as we've understood it for hundreds of thousands of years, versus a collection of cells that will never become a human being, and I don't even believe deserves a status of the word embryo. It could be called a pseudo-embryo, it could be called, you know, some other name should come up from it, because just like test tube babies scared people before, the buzzword embryo scares people today. Cloning scares people today, but this is simply a manipulation of cells that are not equivalent to life as we've always known it.
It gives me a moral compass. I often refer to Abe Lincoln, who said, "When I do good, I feel good. When I do bad, I feel bad. And that is my religion." I think we all have a little voice inside us that will guide us. It may be God, I don't know. But I think that if we shut out all the noise and clutter from our lives and listen to that voice, it will tell us the right thing to do. The Unitarian believes that God is good, and believes that God believes that man is good. Inherently. The Unitarian God is not a God of vengeance. And that is something I can appreciate.
"Neglect - even misstatement - of recent scientific data was also evident in last year's testimony before this subcommittee by the Christopher Reeve Paralysis Foundation. Mr. Reeve, on behalf of the Foundation, testified that adult stem cells are no substitute for embryonic cells because they cannot be "pluripotent" but are confined to a narrow range of specialization. Yet a few weeks after that hearing, researchers funded by the NIH and the Christopher Reeve Paralysis Foundation published a study indicating that adult bone marrow stem cells "may constitute an abundant and accessible cellular reservoir for the treatment of a variety of neurologic diseases." The first sentence of the published study states: "Pluripotent stem cells have been detected in multiple tissues in the adult, participating in normal replacement and repair, while undergoing self-renewal. The authors cite eleven other studies in support of this observation. Their article, prepared under the aegis of Mr. Reeve's foundation, was received for publication in March 2000, before Mr. Reeve testified in April that adult stem cells cannot be pluripotent.
[R]ecent experience has shown that even the most formidable lobbyists cannot derail legislation that has bipartisan and public support. The NRA was not successful in repealing the ban on assault weapons. The American public watched in disbelief as a dozen tobacco company executives testified at a Senate hearing that nicotine is not addictive and denied allegations that nicotine levels were being raised in cigarettes in order to increase addiction. Now we are witnessing the demise of the "Marlboro Man" and "Joe Camel". There are lawsuits in virtually every state by individuals demanding punitive damages against the tobacco companies. Just this week, thousands of government workers petitioned the President to ban smoking in government buildings. I sincerely doubt that the tobacco lobby will be able to stop this initiative. The religious right led by Pat Robertson, Pat Buchanan and the Christian Coalition tried twice unsuccessfully (in 1992 and 1996) to hijack the Republican Party and failed in both attempts. Here again, was a case when a supposedly powerful lobby did not succeed in promoting their agenda.