Eroom’s law — that’s Moore’s law backward — observes that the number of new drugs approved per billion dollars spent on R&D has halved every nine yea… - Peter Thiel

Exposing what is mortal and unsure To all that fortune, death, and danger dare, Even for an eggshell. Rightly to be great Is not to stir without great argument, But greatly to find quarrel in a straw When honor’s at the stake.

If you can recognize competition as a destructive force instead of a sign of value, you’re already more sane than most.

you must think critically about the qualitative characteristics of your business.