If you're too sloppy, then you never get reproducible results, and then you never can draw any conclusions; but if you are just a little sloppy, then… - Max Delbrück

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If you're too sloppy, then you never get reproducible results, and then you never can draw any conclusions; but if you are just a little sloppy, then when you see something startling, (...) you nail it down (...). So I called it the "Principle of Limited Sloppiness".

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About Max Delbrück

Max Ludwig Henning Delbrück (September 4, 1906 – March 9, 1981) was a German-American biophysicist and Nobel laureate.

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Native Name: Max Ludwig Henning Delbrück
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The progress of science is tremendously disorderly, and the motivations that lead to this progress are tremendously varied, and the reasons why scientists go into science, the personal motivations, are tremendously varied. I have said … that science is a haven for freaks, that people go into science because they are misfits, and that it is a sheltered place where they can spin their own yarn and have recognition, be tolerated and happy, and have approval for it.

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The curiosity remains... to grasp more clearly how the same matter, which in physics and chemistry displays orderly and reproducible and relatively simple properties, arranges itself in the most astounding fashions as soon as it is drawn into the orbit of the living organism. The closer one looks at these performances of matter in living organisms the more impressive the show becomes. The meanest living cell becomes a magic puzzle box full of elaborate and changing molecules, and far outstrips all chemical laboratories of man in the skill of organic synthesis performed with ease, expedition, and good judgment of balance.

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