The hormonal genies that have lived unnoticed in the brain since humankind began have escaped; there is no way that they can be put back. - Richard Bergland

If the powerful hormone vasopressin, or ADH, is injected into the blood, the body will retain water. If ADH is injected into the ventricle the opposite happens: the body loses water.

If the question, 'Why is the heart hollow?', had a profound impact on all intellectual disciplines, would you expect any less of the question, 'Why is the brain hollow?'

Many endocrine diseases of the body entail the production of 'crooked molecules'—molecules that are made in the wrong way by the cell. It is fairly common for a cancer cell to begin the production of a 'crooked' hormone that evokes dramatic changes in other body functions.