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" "[S]uppose that the Emperor Karl V. had said to the learned of his day: "I want a method by which I can send a message in a few seconds to that new world, which my mariners take weeks in reaching. ..." ...It required centuries spent in the discovery and classification of new facts before the Atlantic cable became a possibility. It may require the like or even a longer time to unriddle... psychical and biological enigmas... but he who declares that they can never be solved by the scientific method is... as rash as the man of the early sixteenth century would have been had he declared it utterly impossible that the problem of talking across the Atlantic Ocean should ever be solved.
Karl Pearson (27 March 1857 – 27 April 1936) was an influential English mathematician and biostatistician. He founded the world's first university statistics department at University College London in 1911.
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Formerly men had belief as to the supersensuous and thought they had knowledge of the sensuous. The science of the future, while agnostic as to the supersensuous, will replace knowledge by belief in the perceptual sphere, and reserve the term knowledge for the conceptual sphere—the region of their own concepts and ideas...
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The next point to which I turned my attention was the frequency with which the several numbers themselves occurred. ...Each number might be expected to have occurred either 447 or 448 times. ... I found that they fitted to a standard deviation of 15.85 while the theoretical standard was 20.87 giving a difference of 5. ...What is a reasonable amount for the standard deviation of an experiment of this kind to differ from its theoretical value..? The mathematician answers... by finding the standard deviation of the standard deviation. It turned out... to be 2.43... the odds against a divergence as large or larger than 5...were ...21 to 1. In every two years I might expect such a deviation from the most probable results to occur once. ...I ...increased ...by counting the numbers for each week in the month instead of the total month. Here the experimental standard deviation [was] 7.2, the theoretical being 10.34, a difference of 3.14, while the standard deviation between experiment and theory was only 0.60. The odds against a divergence so great as this are... about 2,000,000 to 1.