But how to soothe souls inflamed by the intense torment imposed first by childhood experiences almost too sordid to believe and then, with mechanical… - Gabor Maté

Capitalism is the system that we live under... and for all its economic achievements and scientific breakthroughs — which are very unevenly distributed, with a lot of inequality, which itself is a source of illness — it’s a system that’s based on fundamental assumptions... that people are individualistic and competitive... In fact, from an evolutionary point of view, had we been individualistic and competitive, we never would have evolved. We evolved as communal creatures in close contact with each other, with a lot of mutual support. Now, if you develop a system that’s based on the opposite perspective... then you’re running roughshod over human needs. And so to understand what’s happening on an individual level, you really have to look at what’s happening on a macro level. And this trauma shows up, not only in the personalized, but of course in politics and other areas of our culture. So we really have to look at the larger picture, and not just think that illness is somehow an individual aberration. It’s really a manifestation of a system that is a toxic culture.

Chronic rage, by contrast, floods the system with stress hormones long past the allotted time. Over the long term, such a hormonal surplus, whatever may have instigated it, can make us anxious or depressed; suppress immunity; promote inflammation; narrow blood vessels, promoting vascular disease throughout the body;

In the real world there is no nature vs. nurture argument, only an infinitely complex and moment-by-moment interaction between genetic and environmental effects