One exemplar of that pending disruption is teenager Jack Andraka, who at the age of fourteen single-handedly developed an early-stage detection test … - Salim Ismail

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One exemplar of that pending disruption is teenager Jack Andraka, who at the age of fourteen single-handedly developed an early-stage detection test for pancreatic cancer that costs just three cents. His approach (awaiting peer review) is 26,000 times cheaper, 400 times more sensitive, and 126 times faster than today's diagnostics. Big Pharma has no idea how to deal with Jack, who is one of many wunderkinds emerging globally, all of them with the potential to disrupt great companies and long-established industries. The Jacks of the world bring exponential

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Riaz Shah, the Global Head of Learning at Ernst and Young, trains 100,000 new hires annually. The following image from Riaz is his take on the immune system: Too many people who have worked for a business — especially a large enterprise — are familiar with corporate immune systems.
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Doing anything significant, big, and bold requires a TON of hard work. It also involves countless risks, setbacks, and restarts. While some people are lucky, most success stories require recovering one more time, facing the challenge, and beginning again. Over and over.
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