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The harsh mathematics of polio makes it clear: We cannot maintain a level of one thousand or two thousand cases a year. Either we eradicate polio, or we return to the days of tens of thousands of cases per year. That is no alternative at all. We don't let children die because it is fatiguing to save them. Our commitment as a foundation is to work with partners until no children die from polio.

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I have to say that in 1981, making those decisions, I felt like I was providing enough freedom for 10 years. That is, a move from 64 K to 640 K felt like something that would last a great deal of time. Well, it didn't - it took about only 6 years before people started to see that as a real problem.

One of the wonderful things about the information highway is that virtual equity is far easier to achieve than real-world equity...We are all created equal in the virtual world and we can use this equality to help address some of the sociological problems that society has yet to solve in the physical world,"

Before Paul and I started the company, we had been involved in some large-scale software projects that were real disasters. They just kept pouring people in, and nobody knew how they were going to stabilize the project. We swore to ourselves that we would do better.

This leads to the paradox, that because the disease is only in the poor countries, there is not much investment. For example, there is more money put into baldness drugs, than are put into malaria. Now, baldness, it is a terrible thing [audience laughter] and rich men are afflicted, so that is why that priority is set.