Human nature does change, and the fact that we’ve developed tools to direct that change is quintessentially human. And it must be a nearly universal concomitant to technological growth everywhere in the universe; otherwise there would be no universe. Unless we’re the only technological intelligence in the universe, Julian pointed out; so far there’s no evidence to the contrary. Maybe our own existence is evidence that we’re the first creatures to evolve far enough to hit the reset button. Somebody does have to be first.
But maybe the first is always the last.

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One thing most of us agree on is that the universe exists (people who deny that usually follow some trade other than science), so if some theoretical particle interaction would lead ultimately to the nonexistence of the universe, then you can save a lot of electricity by not trying to demonstrate it.