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" "But this long history of learning how to not fool ourselves — of having utter scientific integrity — is, I’m sorry to say, something that we haven’t specifically included in any particular course that I know of. We just hope you’ve caught on by osmosis. The first principle is that you must not fool yourself — and you are the easiest person to fool. So you have to be very careful about that. After you’ve not fooled yourself, it’s easy not to fool other scientists. You just have to be honest in a conventional way after that.
Richard Phillips Feynman (May 11, 1918 – February 15, 1988) was an American theoretical physicist. He is known for the work he did in the path integral formulation of quantum mechanics, the theory of quantum electrodynamics, the physics of the superfluidity of supercooled liquid helium, and in particle physics, for which he proposed the parton model. For his contributions to the development of quantum electrodynamics, Feynman received the Nobel Prize in Physics in 1965 jointly with Julian Schwinger and Shin'ichirō Tomonaga. Feynman developed a widely used pictorial representation scheme for the mathematical expressions describing the behavior of subatomic particles, which later became known as Feynman diagrams. During his lifetime, Feynman became one of the best-known scientists in the world.
Biography information from Wikiquote
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In general, we look for a new law by the following process: First we guess it. Then we – now don't laugh, that's really true. Then we compute the consequences of the guess to see what, if this is right, if this law that we guessed is right, to see what it would imply. And then we compare the computation results to nature, or we say compare to experiment or experience, compare it directly with observations to see if it works. If it disagrees with experiment, it's wrong. In that simple statement is the key to science. It doesn't make any difference how beautiful your guess is, it doesn't make any difference how smart you are, who made the guess, or what his name is. If it disagrees with experiment, it's wrong. That's all there is to it.
"It is interesting that this thoroughness, which is a virtue, is often misunderstood. When someone says a thing has been done scientifically, often all he means is that it has been done thoroughly. I have heard people talk of the "scientific" extermination of the Jews in Germany. There was nothing scientific about it. It was only thorough. There was no question of making observations and then checking them in order to determine something. In that sense, there were "scientific" exterminations of people in Roman times and in other periods when science was not so far developed as it is today and not much attention was paid to observation. In such cases, people should say "thorough" or "thoroughgoing," instead of "scientific.