Cellular automata are discrete dynamical systems with simple construction but complex self-organizing behaviour. Evidence is presented that all one-d… - Stephen Wolfram

It was the spring of 1978 and I was 18 years old. I’d been publishing papers on particle physics for a few years, and had gotten quite known around the international particle physics community (and, yes, it took decades to live down my teenage-particle-physicist persona). I was in England, but planned to soon go to graduate school in the US, and was choosing between Caltech and Princeton. And one weekend afternoon when I was about to go out, the phone rang. In those days, it was obvious if it was an international call. “This is Murray Gell-Mann”, the caller said, then launched into a monologue about why Caltech was the center of the universe for particle physics at the time.

I think Computation is destined to be the defining idea of our future.

[S]cience has become used to... using the little... pockets of computational reducibility ([A]n inevitable consequence of computational irreducibility... There have to be these pockets ...scattered around.) to be able to find those cases where you can jump ahead.