That is the principle of science. If there is an exception to any rule, and if it can be proved by observation, that rule is wrong. - Richard Feynman

We have found it of paramount importance that in order to progress we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty — some most unsure, some nearly sure, but none absolutely certain.

Of course, I am interested, but I would not dare to talk about them. In talking about the impact of ideas in one field on ideas in another field, one is always apt to make a fool of oneself. In these days of specialization there are too few people who have such a deep understanding of two departments of our knowledge that they do not make fools of themselves in one or the other.

We cannot do it in this way for two reasons. First, we do not yet know all the basic laws: there is an expanding frontier of ignorance. Second, the correct statement of the laws of physics involves some very unfamiliar ideas which require advanced mathematics for their description.