And why could all this not be fulfilled in the case of an organism composed of a moderate number of atoms only and sensitive already to the impact of… - Erwin Schrödinger

Now I believe that the increasing mechanization and ‘stupidization’ of most manufacturing processes involve the serious danger of a general degeneration of our organ of intelligence. The more the chances in life of the clever and of the unresponsive worker are equalled out by the repression of handicraft and the spreading of tedious and boring work on the assembly line, the more will a good brain, clever hands and a sharp eye become superfluous. Indeed the unintelligent man, who naturally finds it easier to submit to the boring toil, will be favoured; he is likely to find it easier to thrive, to settle down and to beget offspring. The result may easily amount even to a negative selection as regards talents and gifts.

we never experiment with just one electron or atom or (small) molecule. In thought-experiments we sometimes assume that we do.

In no case is there a loss of personal existence to deplore. Nor will there ever be.